Protein design: a perspective from simple tractable models.
Publication information:
Shakhnovich, E. Protein design: a perspective from simple tractable models. Folding & design 3, R45–58 (1998).
Abstract
Recent progress in computational approaches to protein design builds on advances in statistical mechanical protein folding theory. Here, the number of sequences folding into a given conformation is evaluated and a simple condition for a protein model's designability is outlined.